PDRN In Professional Skin Care

PDRN in Professional Skincare: From Sushi Talk to Skin Transformation

If you’ve been hanging out in the world of advanced skincare, you might’ve heard whispers of an ingredient that sounds more like sushi than serum: PDRN — short for polydeoxyribonucleotide. This not-so-new bioactive is having a major moment in clinical skincare, and spoiler alert — it’s not just hype.

Originally extracted from salmon DNA (wait—salmon what?!), PDRN is a standout example of marine biotech meeting regenerative medicine. While the origin story might raise an eyebrow, the science is rock solid. With over 30 years of medical research under its belt, PDRN has gone from treating radiation injuries post-Chernobyl to becoming a go-to for post-procedure recovery and barrier repair.

So, What Is PDRN, Really?

PDRN is like a chain of tiny DNA fragments that the skin recognizes. With a 95% compatibility rate to human DNA, it’s basically a biological doppelgänger — able to easily communicate with the skin and jumpstart healing on a cellular level. It activates adenosine A2A receptors, kicks off growth factor release, improves microcirculation, and soothes inflammation. In short: it’s a multitasking repair wizard.

It is no wonder 88% of Korean dermatologists named PDRN-based boosters among their top-used injectables by 2023 — and it all started with Rejuran Healer in 2014. The clinical results speak for themselves.

What the Research Tells Us

Let’s skip the fluff and get into the data:

Read more here: https://www.ascpskindeepdigital.com/i/1539961-autumn-2025/46?

CycloRetin: The Summer-Safe Retinol Alternative

As estheticians, we’ve long walked the line between results and tolerance—balancing powerful actives like retinol with the unique needs of each client’s skin. As the seasons change, so do our skincare needs—and summer brings its own set of challenges. Increased sun exposure, higher temperatures, and time spent outdoors can influence how our skin reacts to certain ingredients. One of the most debated summer skincare topics? Whether it's safe—or wise—to use retinol during the sunniest time of the year. While traditional retinoids remain a gold standard in anti-aging, they also come with familiar frustrations: redness, peeling, and the seasonal dilemma of sun sensitivity.  And if not, what alternatives actually work? This is where CycloRetin™ steps in—not just as a “gentler alternative,” but as a scientifically sound, bioactive ingredient that may reshape how we approach vitamin A pathways altogether. But is it really safe (and smart) to use in the summer? Let’s take a closer look.

The Problem With Retinol in Summer

Retinol, a vitamin A derivative, is a tried-and-true powerhouse when it comes to stimulating cell turnover, boosting collagen, and targeting signs of aging and acne.  However, it comes with a list of side effects that are only exacerbated by sun exposure.

If you’re already cycling retinol out of your clients’ routines during the sunnier months, you’re not alone.

Read more Here: https://www.ascpskindeepdigital.com/i/1537409-summer-2025/40?

Off-Label Use of Skincare Products: Innovation, Risk, and the Science Behind It

We all know skincare is a dynamic and ever-evolving industry, where professionals and

consumers alike are constantly on the look-out for innovative ways to maximize the

benefits of products and routines. While most products are formulated and marketed for

specific uses, there is a fascinating world where people repurpose certain products

outside of their original intention. It is not a new practice, nor is it reserved just for the

skincare space, but what is “off label use”, really?

One shining example of using a product off-label and outside of its original intention is

Ozempic for weight loss. Unless you have been living under a rock (and with no social

media or TV), you are undoubtedly aware glp-1 pharmaceuticals were originally

prescribed as diabetes drugs yet have unexpectedly become a game-changer in weight

management. And then, of course, we have the “My Big Fat Greek Wedding” approach

of “put a little Windex” on anything and everything. Or how about the age-old old wives’

tale of using diaper rash cream to soothe irritated skin—an unconventional but

surprisingly effective solution that is passed down as a secret remedy for generations.

In the world of skincare, similar unconventional uses of products have gained traction,

often blurring the line between innovation and risk.

But is off label use always safe? And when does experimentation become a

dermatological disaster? Let’s take a closer look into the science behind off-label

skincare, its risks and benefits, and what skincare professionals should consider before

recommending alternative uses.

What Is Off-Label Skincare?

https://www.ascpskindeepdigital.com/i/1533707-spring-2025/72?

Skin Deep Magazine - Autumn 2024

The Demand (and Benefits) of Epidermal Growth Factor

In this Skin Deep feature, I demystify Epidermal Growth Factors (EGFs)—proteins with powerful regenerative potential that are making waves in both professional treatments and at-home skincare. From accelerating cell turnover to boosting collagen and aiding post-procedure recovery, EGFs offer advanced support for aging, damaged, or compromised skin. This article breaks down how they work, the challenges of effective formulation, and practical ways to integrate them into a results-driven skincare practice.

Indie Stylist Magazine - Volume 5, Issue 2 - 2024

How Well Do You Know Your Hair Dye? Paraphenylenediamine and its drawbnacks

In this eye-opening article for Indie Hairstylist Magazine, I unpack the hidden dangers of paraphenylenediamine (PPD)—a powerful yet potentially harmful ingredient found in many dark hair dyes. From severe allergic reactions to long-term health risks for beauty professionals, this piece explores the science, symptoms, and safer alternatives to help stylists and clients make informed choices. A must-read for any colorist committed to safe, responsible beauty.

Skin Deep - Summer 2024

Glycerin: Diving into a timeless, skin-quenching ingredient.

In this Skin Deep Summer Issue feature, I spotlight glycerin—an unassuming yet powerhouse ingredient that’s been quietly transforming skincare for centuries. From enhancing hydration and fortifying the skin barrier to accelerating healing and smoothing fine lines, glycerin proves that simple ingredients can deliver profound results. This article traces its origins, explains its function, and highlights why it remains a staple in everything from serums to cleansers across all skin types.

Indie Stylist Magazine - Volume 5, Issue 1 2024

Not All Bacteria Is Bad Bacteria - The connection between probiotics and hair health.

In this Indie Stylist article, I explore the emerging science behind probiotics as a powerful ally for scalp and hair health. From balancing the scalp microbiome and reducing inflammation to boosting hair growth and shine, probiotics—whether applied topically, consumed orally, or added through diet—offer a holistic approach to cultivating strong, vibrant hair. Rooted in wellness and backed by science, this piece reveals why a flourishing colony of friendly bacteria might be the secret weapon in every stylist’s toolkit.

Skin Deep Magazine - Spring 2024

Niacinamide: Don’t Call It a Comeback

In this Skin Deep Winter feature, I revisit niacinamide, the quietly consistent multitasker that’s finally getting the recognition it deserves. From boosting barrier function and calming inflammation to balancing oil production, fading hyperpigmentation, and fighting visible signs of aging, this water-soluble form of vitamin B3 checks every skincare box. With a proven track record and renewed research backing, niacinamide isn’t riding a comeback—it’s simply reclaiming its crown as a skin health staple.